Are You Ready for Relfydess?
The New Liquid Toxin That Could Change Aesthetic Treatments
At Freeda Clinic, we’re always on the lookout for the most effective, innovative treatments for our clients — and there’s a new name on the block that’s making waves in the world of aesthetics: Relfydess.
Developed by Galderma, Relfydess (RelabotulinumtoxinA) is a next-generation, ready-to-use liquid botulinum toxin. Unlike traditional toxins like Azzalure or Botox, which require mixing and come with added complexing proteins, Relfydess uses cutting-edge PEARL™ Technology to deliver a pure, stabilized molecule. This seemingly small change may have big implications — including longer-lasting effects and reduced risk of immune resistance over time.
What Makes Relfydess So Exciting?
The results from the recent READY-4 clinical trial are promising. Repeated injections for both frown lines and crow’s feet showed sustained results and high patient satisfaction — a clear indicator that this product is more than just a trend.
Let’s break down the key points:
•Fast Results
•Visible improvements can begin in as little as 24 hours. Around 40% of patients noticed a difference on day one.
•Peak effect is typically seen between Day 7–14, with over 90% experiencing significant improvement in frown lines.
•Long-Lasting Results
•Around 75% of patients maintained visible improvements at 6 months, with some seeing effects last up to 12 months.
This is notably longer than traditional toxins like Azzalure or Botox, which typically last 3–4 months.
How Is Relfydess Administered?
Relfydess is delivered in much the same way as Azzalure — via fine needle into targeted facial muscles by a trained medical professional. However, the big difference? It comes pre-mixed in liquid form, which reduces preparation errors and offers more consistent results.
Off-label uses (like jawline slimming and neck treatments) are still possible, and it’s administered with the same care and precision our clients expect.
Client Experience: What You Need to Know
While Relfydess offers some exciting benefits, it’s important to understand how it compares to what many of our clients are already used to with Azzalure.
• Discomfort Level: Relfydess is known to cause more discomfort during injection, with many patients rating it 9 out of 10 on the discomfort scale. If you're sensitive to needles or prefer a gentler treatment experience, Azzalure may be a more comfortable option.
• Side Effects: Similar to other botulinum toxin treatments, Relfydess can cause mild bruising, redness, or headaches, though these effects are typically short-lived.
• Patient Satisfaction: Despite the higher discomfort, over 84% of patients reported being highly satisfied with their results from Relfydess — especially due to how quickly it works and how long it lasts.
Who Might Benefit Most from Relfydess?
Relfydess may be ideal if you:
• Want quicker results, possibly within 24 hours.
• Prefer longer intervals between treatments (6–12 months).
• Are concerned about toxin resistance due to frequent treatments.
• Are looking for a reliable option that reduces reconstitution variability.
It’s especially suited for treating:
• Moderate to severe frown lines (glabellar lines)
• Crow’s feet, with long-term results backed by clinical data
Azzalure vs. Relfydess: Which One Is Right for You?
While Relfydess offers some exciting advancements, at Freeda Clinic, Azzalure remains our preferred option for now.
Here’s why:
• Comfort: Azzalure is less painful during treatment — a key consideration for many clients.
• Cost: Relfydess is slightly more expensive, due in part to its longer duration.
• Proven Results: Azzalure continues to deliver reliable, safe, and effective results with a well-known safety profile.
We’ve recently introduced Relfydess as part of our commitment to offering the latest and most advanced aesthetic treatments. While it's still early days, we’re excited to see how it performs for our clients who are looking for longer-lasting results or are curious to try the newest innovations in toxin treatments.
That said, for those who value a more comfortable injection experience and a proven track record of consistent, affordable results, Azzalure continues to be a trusted favourite at Freeda Clinic.
Whether you're curious about trying Relfydess or sticking with your trusted favourite like Azzalure, we're here to guide you every step of the way.
Book your free consultation today —let’s refresh, refine, and reveal your most confident self.
